diff --git a/public/index.html b/public/index.html
index 65983e7..47688a7 100644
--- a/public/index.html
+++ b/public/index.html
@@ -39,8 +39,8 @@
   <% if (process.env.VUE_APP_NODE_ENV === 'dev') { %>
     <script>
     //http://121.36.16.195:9002/huimu-admin/swagger-ui/index.html
-    // window.SITE_CONFIG['apiURL'] = 'http://47.110.224.240:8036/xiangan-crf';
-    window.SITE_CONFIG['apiURL'] = 'http://192.168.0.168:8036/xiangan-crf';
+    window.SITE_CONFIG['apiURL'] = 'http://47.110.224.240:8036/xiangan-crf';
+    // window.SITE_CONFIG['apiURL'] = 'http://192.168.0.168:8036/xiangan-crf';
     // window.SITE_CONFIG['apiURL'] = 'http://192.168.4.174:8036/xiangan-crf';
     </script>
   <% } %>
diff --git a/src/components/360View/medicalRecord/index.vue b/src/components/360View/medicalRecord/index.vue
index 99808d8..9524f79 100644
--- a/src/components/360View/medicalRecord/index.vue
+++ b/src/components/360View/medicalRecord/index.vue
@@ -10,6 +10,7 @@
         :patient-id="patientId"
         :is-search="isSearch"
         :only-read="onlyRead"
+        `
         :is-platform="isPlatform"
         :form-list="formList"
         :cur-index="curIndex"
@@ -337,6 +338,7 @@ export default {
       }
       this.$http.post('/case/update', params).then(data => {
         this.updateForm()
+        this.$store.commit('destroyPlugin')
       })
     },
     // 删除同意书
diff --git a/src/page-subspecialty/views/modules/formList/DrugInjection.vue b/src/page-subspecialty/views/modules/formList/DrugInjection.vue
index 6fccbbe..3f72dc5 100644
--- a/src/page-subspecialty/views/modules/formList/DrugInjection.vue
+++ b/src/page-subspecialty/views/modules/formList/DrugInjection.vue
@@ -160,6 +160,8 @@
 </template>
 
 <script>
+import emptySign from '@static/js/emptySign'
+
 export default {
   name: 'DrugInjection',
   props: {
@@ -297,6 +299,10 @@ export default {
     },
     // 保存
     handleSaveTable() {
+      if (this.minorPatientSignM === emptySign || this.minorKinSignM === emptySign) {
+        this.$message.error('签字未成功请重新签字后再保存')
+        return
+      }
       this.confirmData.patientSign = this.minorPatientSignM
       this.confirmData.familySign = this.minorKinSignM
       const data = JSON.stringify(this.confirmData)
diff --git a/src/page-subspecialty/views/modules/formList/InformedConsent.vue b/src/page-subspecialty/views/modules/formList/InformedConsent.vue
index 9148fa7..0e29417 100644
--- a/src/page-subspecialty/views/modules/formList/InformedConsent.vue
+++ b/src/page-subspecialty/views/modules/formList/InformedConsent.vue
@@ -151,6 +151,8 @@
   </div></template>
 
 <script>
+import emptySign from '@static/js/emptySign'
+
 export default {
   name: 'InformedConsent',
   props: {
@@ -577,6 +579,10 @@ export default {
     },
     // 保存
     handleSaveTable() {
+      if (this.informPatientSign === emptySign) {
+        this.$message.error('签字未成功请重新签字后再保存')
+        return
+      }
       if (!this.confirmData.eyeType) {
         this.$message.error('请选择眼别')
         this.$refs.eyeTypeRef.focus()
diff --git a/src/page-subspecialty/views/modules/formList/InjectionTherapy.vue b/src/page-subspecialty/views/modules/formList/InjectionTherapy.vue
index f7db792..a32716b 100644
--- a/src/page-subspecialty/views/modules/formList/InjectionTherapy.vue
+++ b/src/page-subspecialty/views/modules/formList/InjectionTherapy.vue
@@ -97,6 +97,8 @@
 </template>
 
 <script>
+import emptySign from '@static/js/emptySign'
+
 export default {
   name: 'InjectionTherapy',
   props: {
@@ -180,10 +182,13 @@ export default {
     },
     // 保存
     handleSaveTable() {
+      if (this.minorPatientSignM === emptySign || this.minorKinSignM === emptySign) {
+        this.$message.error('签字未成功请重新签字后再保存')
+        return
+      }
       this.confirmData.patientSign = this.minorPatientSignM
       this.confirmData.familySign = this.minorKinSignM
       const data = JSON.stringify(this.confirmData)
-      console.log(data)
       this.$emit('handleSaveTable', data)
     },
     // 获取同意书详情
diff --git a/src/page-subspecialty/views/modules/formList/MinorOperation.vue b/src/page-subspecialty/views/modules/formList/MinorOperation.vue
index 0801475..6222ede 100644
--- a/src/page-subspecialty/views/modules/formList/MinorOperation.vue
+++ b/src/page-subspecialty/views/modules/formList/MinorOperation.vue
@@ -167,6 +167,8 @@
 </template>
 
 <script>
+import emptySign from '@static/js/emptySign'
+
 export default {
   name: 'MinorOperation',
   props: {
@@ -303,6 +305,10 @@ export default {
     },
     // 保存
     handleSaveTable() {
+      if (this.minorPatientSignM === emptySign || this.minorKinSignM === emptySign) {
+        this.$message.error('签字未成功请重新签字后再保存')
+        return
+      }
       this.confirmData.patientSign = this.minorPatientSignM
       this.confirmData.familySign = this.minorKinSignM
       const data = JSON.stringify(this.confirmData)
diff --git a/src/page-subspecialty/views/modules/formList/StyeForm.vue b/src/page-subspecialty/views/modules/formList/StyeForm.vue
index 7f873f5..c9ca1b2 100644
--- a/src/page-subspecialty/views/modules/formList/StyeForm.vue
+++ b/src/page-subspecialty/views/modules/formList/StyeForm.vue
@@ -35,16 +35,33 @@
           诊断：<el-input v-model="confirmData.diagnose" style="flex: 1" />
         </div>
         <div class="flex" style="margin: 8px 0">
-          手术名称：
-          <el-select v-model="confirmData.operationName" style="flex: 1" clearable placeholder="">
+          眼别：
+          <el-select
+            v-model="confirmData.eyeType"
+            filterable
+            allow-create
+            placeholder=""
+            style="flex: 1"
+          >
             <el-option
-              v-for="item in types"
-              :key="item.id"
+              v-for="item in options"
+              :key="item.value"
               :label="item.label"
               :value="item.value"
             />
           </el-select>
         </div>
+        <div class="flex" style="margin: 8px 0">
+          手术名称：
+          <el-select v-model="confirmData.operationName" style="flex: 1" filterable allow-create clearable placeholder="">
+            <el-option
+              v-for="item in types"
+              :key="item.name"
+              :label="item.value"
+              :value="item.name"
+            />
+          </el-select>
+        </div>
         <div class="flex">
           麻醉方式：<el-input v-model="confirmData.narcotism" style="flex: 1" />
         </div>
@@ -76,12 +93,12 @@
       </div>
       <div>
         在向患方说明各治疗方案并告知利弊后，患方基于当前病情需要，经慎重考虑，自愿选择
-        <el-select v-model="confirmData.treatOperate" style="width: 200px" clearable placeholder="">
+        <el-select v-model="confirmData.treatOperate" style="width: 260px" filterable allow-create clearable placeholder="">
           <el-option
             v-for="item in types"
-            :key="item.id"
-            :label="item.label"
-            :value="item.value"
+            :key="item.name"
+            :label="item.value"
+            :value="item.name"
           />
         </el-select>手术。
       </div>
@@ -166,6 +183,8 @@
 </template>
 
 <script>
+import emptySign from '@static/js/emptySign'
+
 export default {
   name: 'StyeForm',
   props: {
@@ -187,28 +206,17 @@ export default {
   },
   data() {
     return {
-      types: [
-        {
-          label: '麦粒肿切除术',
-          value: 1,
-          id: '11'
-        },
-        {
-          label: '霰粒肿切除术',
-          value: 2,
-          id: '22'
-        },
-        {
-          label: '肉芽肿切除术',
-          value: 3,
-          id: '33'
-        },
-        {
-          label: '眼睑肿物切除术',
-          value: 4,
-          id: '44'
-        }
-      ],
+      options: [{
+        value: 'OD',
+        label: 'OD'
+      }, {
+        value: 'OS',
+        label: 'OS'
+      }, {
+        value: 'OU',
+        label: 'OU'
+      }],
+      types: [],
       content: [
         '1.麻醉意外，极少数人对麻醉药物过敏，引起药物反应。',
         '2.手术操作过程中难以避免的组织或器官损伤：如结膜、角膜、肌肉、神经、血管、邻近器官等，并导致其他并发症的发生。',
@@ -252,6 +260,7 @@ export default {
             isSelect: false
           }
         ],
+        eyeType: '',
         diagnose: '',
         operationName: '',
         narcotism: '局部浸润麻醉',
@@ -290,6 +299,11 @@ export default {
     signClick(index) {
       this.$store.commit('beginSign', index)
     },
+    queryOperations() {
+      this.$http.get('mzbl/getMlzZyzqtysProject').then(data => {
+        this.types = data.data.data
+      })
+    },
     queryDiagnostic() {
       this.$http.get('/mzbl/getLastDiagnostic', { params: {
         patientId: this.patientDetail.patientId
@@ -303,6 +317,10 @@ export default {
     },
     // 保存
     handleSaveTable() {
+      if (this.minorPatientSign === emptySign || this.minorKinSign === emptySign) {
+        this.$message.error('签字未成功请重新签字后再保存')
+        return
+      }
       this.confirmData.patientSign = this.minorPatientSign
       this.confirmData.familySign = this.minorKinSign
       const data = JSON.stringify(this.confirmData)
@@ -313,6 +331,7 @@ export default {
       this.$http.get('/case/getCaseById', { params: {
         id: this.caseId
       }}).then(data => {
+        this.queryOperations()
         const detail = data.data.data
         if (detail.jsonText) {
           this.confirmData = JSON.parse(detail.jsonText)
diff --git a/src/page-subspecialty/views/modules/formList/childrenLacrimal.vue b/src/page-subspecialty/views/modules/formList/childrenLacrimal.vue
index c1097da..a399ca3 100644
--- a/src/page-subspecialty/views/modules/formList/childrenLacrimal.vue
+++ b/src/page-subspecialty/views/modules/formList/childrenLacrimal.vue
@@ -110,6 +110,8 @@
 </template>
 
 <script>
+import emptySign from '@static/js/emptySign'
+
 export default {
   name: 'Lacrimal',
   props: {
@@ -247,6 +249,10 @@ export default {
     },
     // 保存
     async handleSaveTable() {
+      if (this.childrenSign === emptySign) {
+        this.$message.error('签字未成功请重新签字后再保存')
+        return
+      }
       this.confirmData.patientSign = this.childrenSign
       const params = {
         id: this.caseId,
diff --git a/src/page-subspecialty/views/modules/formList/conjunctivalOperation.vue b/src/page-subspecialty/views/modules/formList/conjunctivalOperation.vue
index a3f29a8..25cdc94 100644
--- a/src/page-subspecialty/views/modules/formList/conjunctivalOperation.vue
+++ b/src/page-subspecialty/views/modules/formList/conjunctivalOperation.vue
@@ -114,6 +114,8 @@
 </template>
 
 <script>
+import emptySign from '@static/js/emptySign'
+
 export default {
   name: 'ConjunctivalOperation',
   props: {
@@ -291,6 +293,10 @@ export default {
     },
     // 保存
     async handleSaveTable() {
+      if (this.conPatientSign === emptySign || this.conKinSign === emptySign) {
+        this.$message.error('签字未成功请重新签字后再保存')
+        return
+      }
       this.confirmData.patientSign = this.conPatientSign
       this.confirmData.familySign = this.conKinSign
       const params = {
diff --git a/src/page-subspecialty/views/modules/formList/cornealForeign.vue b/src/page-subspecialty/views/modules/formList/cornealForeign.vue
index 66b915b..2673664 100644
--- a/src/page-subspecialty/views/modules/formList/cornealForeign.vue
+++ b/src/page-subspecialty/views/modules/formList/cornealForeign.vue
@@ -142,6 +142,8 @@
 </template>
 
 <script>
+import emptySign from '@static/js/emptySign'
+
 export default {
   name: 'ConjunctivalOperation',
   props: {
@@ -284,6 +286,10 @@ export default {
     },
     // 保存
     async handleSaveTable() {
+      if (this.cornealPatientSign === emptySign || this.cornealKinSign === emptySign) {
+        this.$message.error('签字未成功请重新签字后再保存')
+        return
+      }
       this.confirmData.patientSign = this.cornealPatientSign
       this.confirmData.familySign = this.cornealKinSign
       const params = {
diff --git a/src/page-subspecialty/views/modules/formList/mraForm.vue b/src/page-subspecialty/views/modules/formList/mraForm.vue
index 87689f9..7079278 100644
--- a/src/page-subspecialty/views/modules/formList/mraForm.vue
+++ b/src/page-subspecialty/views/modules/formList/mraForm.vue
@@ -181,6 +181,8 @@
 </template>
 
 <script>
+import emptySign from '@static/js/emptySign'
+
 export default {
   name: 'MraForm',
   props: {
@@ -315,6 +317,14 @@ export default {
       this.handleSaveTable()
     },
     handleSaveTable() {
+      if (this.fundusDocSign === emptySign ||
+          this.kinSign === emptySign ||
+          this.performerSign === emptySign ||
+          this.checkerSign === emptySign
+      ) {
+        this.$message.error('签字未成功请重新签字后再保存')
+        return
+      }
       const start = this.$moment(this.startTime).format('yyyy-MM-DD HH:mm')
       const end = this.$moment(this.endTime).format('yyyy-MM-DD HH:mm')
       this.formData.negativeTime = start + '~' + end
diff --git a/src/page-subspecialty/views/modules/formList/puncture.vue b/src/page-subspecialty/views/modules/formList/puncture.vue
index b0fdd33..3bdd8ff 100644
--- a/src/page-subspecialty/views/modules/formList/puncture.vue
+++ b/src/page-subspecialty/views/modules/formList/puncture.vue
@@ -119,6 +119,8 @@
 </template>
 
 <script>
+import emptySign from '@static/js/emptySign'
+
 export default {
   name: 'Puncture',
   props: {
@@ -279,6 +281,10 @@ export default {
     },
     // 保存
     async handleSaveTable() {
+      if (this.puncturePatientSign === emptySign || this.punctureKinSign === emptySign) {
+        this.$message.error('签字未成功请重新签字后再保存')
+        return
+      }
       this.confirmData.patientSign = this.puncturePatientSign
       this.confirmData.familySign = this.punctureKinSign
       const params = {
diff --git a/src/page-subspecialty/views/modules/optometryManagement/seeDoctor/CornealReview.vue b/src/page-subspecialty/views/modules/optometryManagement/seeDoctor/CornealReview.vue
index 1216bb6..ed86193 100644
--- a/src/page-subspecialty/views/modules/optometryManagement/seeDoctor/CornealReview.vue
+++ b/src/page-subspecialty/views/modules/optometryManagement/seeDoctor/CornealReview.vue
@@ -138,6 +138,7 @@
 
 <script>
 import headTemplate from '@/components/head'
+import emptySign from '@static/js/emptySign'
 export default {
   name: 'CornealReview',
   components: {
@@ -491,6 +492,10 @@ export default {
       this.handleSaveTable()
     },
     async handleSaveTable() {
+      if (this.checkSign === emptySign) {
+        this.$message.error('签字未成功请重新签字后再保存')
+        return
+      }
       this.formData.checkResult = this.formData.checkResult.length ? this.formData.checkResult.join(',') : ''
       this.formData.jmdxtOd = this.formData.jmdxtOd.length ? this.formData.jmdxtOd.join(',') : ''
       this.formData.jmdxtOs = this.formData.jmdxtOs.length ? this.formData.jmdxtOs.join(',') : ''
diff --git a/src/page-subspecialty/views/modules/optometryManagement/seeDoctor/informBook/notice-book.vue b/src/page-subspecialty/views/modules/optometryManagement/seeDoctor/informBook/notice-book.vue
index 0d0548b..08824b2 100644
--- a/src/page-subspecialty/views/modules/optometryManagement/seeDoctor/informBook/notice-book.vue
+++ b/src/page-subspecialty/views/modules/optometryManagement/seeDoctor/informBook/notice-book.vue
@@ -132,6 +132,7 @@
 </template>
 <script>
 import headTemplate from '@/components/head'
+import emptySign from '@static/js/emptySign'
 export default {
   components: {
     headTemplate
@@ -231,6 +232,13 @@ export default {
     },
     // 保存、修改告知书
     saveEditNotice() {
+      if (this.doctorSign2 === emptySign ||
+          this.guardianSign2 === emptySign ||
+          this.patientSign2 === emptySign ||
+          this.optomSign2 === emptySign) {
+        this.$message.error('签字未成功请重新签字后再保存')
+        return
+      }
       const params = {
         noticeType: 1,
         patientId: this.patientId,
diff --git a/src/page-subspecialty/views/modules/optometryManagement/seeDoctor/informBook/rgp-book.vue b/src/page-subspecialty/views/modules/optometryManagement/seeDoctor/informBook/rgp-book.vue
index 59893da..5b166a8 100644
--- a/src/page-subspecialty/views/modules/optometryManagement/seeDoctor/informBook/rgp-book.vue
+++ b/src/page-subspecialty/views/modules/optometryManagement/seeDoctor/informBook/rgp-book.vue
@@ -120,6 +120,7 @@
 </template>
 <script>
 import headTemplate from '@/components/head'
+import emptySign from '@static/js/emptySign'
 export default {
   components: {
     headTemplate
@@ -219,6 +220,13 @@ export default {
     },
     // 保存、修改告知书
     saveEditNotice() {
+      if (this.optomSign === emptySign ||
+          this.doctorSign === emptySign ||
+          this.patientSign === emptySign ||
+          this.guardianSign === emptySign) {
+        this.$message.error('签字未成功请重新签字后再保存')
+        return
+      }
       const params = {
         noticeType: 2,
         patientId: this.patientId,
diff --git a/static/js/emptySign.js b/static/js/emptySign.js
new file mode 100644
index 0000000..8ea3f44
--- /dev/null
+++ b/static/js/emptySign.js
@@ -0,0 +1,2 @@
+const emptySign = "data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAtMAAAFMCAYAAAAJLDA6AAAAAXNSR0IArs4c6QAAAARnQU1BAACxjwv8YQUAAAAJcEhZcwAAEnQAABJ0Ad5mH3gAAAO5SURBVHhe7cEBDQAAAMKg909tDwcEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAF2qorgABUDpN1AAAAABJRU5ErkJggg=="
+export default emptySign
\ No newline at end of file